Combination of Topiramate and Empagliflozin is Considered a Good Option for the Treatment of Obesity

Ministry of Health and Population, Egypt

Status: Completed

Conditions: Obesity

Treatments: Drug: The intervention being studied

Study type: Observational

Funder types: Other

Identifiers

NCT04043702

12345678

Details and patient eligibility

About

The aim was to show if a combination of topiramate and empagliflozin have the greatest weight decreasing effect in comparison to each drug alone and to group with no treatment( control group).

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Full description

The aim was to show if a combination of topiramate and empagliflozin have the greatest weight decreasing effect in comparison to each drug alone and to group with no treatment( control group).

Materials and methods 200 obese patients 4 groups. had been monitored in a private clinic, each group 50 patients number, with 35 females and 15 males who were already on treatment.

Enrollment: 200 patients

Sex: All

Ages: 30 to 55 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. stable weight in the previous 6 months.
2. a sedentary lifestyle.
3. no history of diabetes mellitus.
4. taking medication that affects appetite, or weight within the past 6 months

Exclusion criteria

1. severe anemia
2. hypothyroidism and hyperthyroidism
3. Diabetes mellitus
4. moderate to severe liver or kidney disease
5. body mass index less than 30

Trial design

200 participants in 4 patient groups

on topiramate

Description:

"topiramate", "conviban®" group vs no treatment ( control group).

Treatment:

Drug: The intervention being studied

on empagliflozine

Description:

"empagliflozine", "jardiance®" vs no treatment ( control group).

Treatment:

Drug: The intervention being studied

on topiramate plus empagliflozine

Description:

all patients' vs no treatment ( control group).

Treatment:

Drug: The intervention being studied

no treatment

Description:

all patients' vs no treatment ( control group).

Treatment:

Drug: The intervention being studied