Combinations of Pharmacologic Smoking Cessation Treatments

US Department of Veterans Affairs (VA)

Status and phase: Completed; Phase 1

Conditions: Smoking

Treatments: Drug: Nicotine Patch; Drug: Bupropion; Drug: Mecamylamine

Study type: Interventional

Funder types: Other U.S. Federal agency

Identifiers

NCT00018187

ADRD-011-98S

Details and patient eligibility

About

The purpose of this study is to test the effectiveness of a combination of the drugs bupropion and mecamylamine along with a nicotine patch as a therapy for smoking cessation.

Sex: All

Ages: 20 to 40 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Subjects must be a smoker between 20 and 40 years old, have smoked at least 20 cigarettes per day for at least 2 years, wish to stop smoking and be in good general health

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)