Combined Amniotic Membrane and Platelet Rich Plasma Clot for Management of Central Corneal Perforation

M

Minia University

Status

Completed

Conditions

Corneal Perforation

Treatments

Procedure: Platelet rich plasma clot implantation
Procedure: Wound closure with amniotic membrane

Study type

Interventional

Funder types

Other

Identifiers

NCT03500796
56-2/2018

Details and patient eligibility

About

Use of amniotic membrane(AMT) and platelet rich plasma (PRP) clot for closure of central corneal perforation

Full description

Use of amniotic membrane and platelet rich plasma clot for closure of central corneal perforation either post infective or posttraumatic

Enrollment

10 patients

Sex

All

Volunteers

No Healthy Volunteers

Inclusion criteria

  • central corneal perforation

Exclusion criteria

  • active infection
  • posterior segment pathology
  • non seeing eye

Trial design

Primary purpose

Treatment

Allocation

N/A

Interventional model

Single Group Assignment

Masking

None (Open label)

10 participants in 1 patient group

Corneal perforation patients
Other group
Description:
Patients who had/impeding corneal perforation due to melting of the cornea after infection with a corneal pathogen (bacterial or viral), with no previous surgical intervention. Patients will undergo: Platelet rich plasma clot implantation Wound closure with amniotic membrane
Treatment:
Procedure: Wound closure with amniotic membrane
Procedure: Platelet rich plasma clot implantation

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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