Combined and Isolated Effects of Sleep Deprivation and Alcohol Intake on Exercise Performance in Humans.

Federal University of Rio Grande do Sul

Status: Completed

Conditions: Alcohol Intake; Sleep Deprivation

Treatments: Other: Alcohol intake; Other: Sleep deprivation

Study type: Interventional

Funder types: Other

Identifiers

NCT02117193

UFRGS 366465

Details and patient eligibility

About

Although the effects of acute alcohol intake and sleep deprivation on exercise performance lacks evidence in the literature, in many situations, they occur simultaneously. Once the alcohol affects physiological processes, the processes that occur during sleep can be impaired, such as: suppression of GH release, action of neurotransmitters and neuromodulators in the CNS, changes in the proportion of sleep stages and may lead to suppression of REM sleep. These changes promote a significant functional impairment such as a reduction in alertness and modification in reaction time, which affects the performance of any activity of daily and professional life. However, the combined effects on the physical performance variables, such as aerobic and neuromuscular performance lack of evidence in the literature.

Full description

Ten subjects were randomized in four situations after familiarization and control situation: (1) alcohol intake combined with sleep normal; (2) alcohol intake combined with sleep deprivation; (3) placebo intake combined with sleep normal and (4) placebo intake combined with sleep deprivation.

Enrollment: 10 patients

Sex: Male

Ages: 18 to 30 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Physical active men

Exclusion criteria

• AUDIT questionnaire above 15 points
• Nocturnal Chronotype
• Skeletal muscle injuries in upper and lower limb
• Metabolic and cardiovascular disease

Trial design

10 participants in 2 patient groups, including a placebo group

Alcohol intake

Placebo Comparator group

Description:

1 g/kg of etanol combined. Beer without alcohol in the same volume will be used to placebo condition.

Treatment:

Other: Alcohol intake

Other: Sleep deprivation

sleep deprivation

Active Comparator group

Description:

one night of sleep deprivation will be compared to 8h of normal sleep.

Treatment:

Other: Alcohol intake

Other: Sleep deprivation