Combined Anticholinergic Medication and Sacral Neuromodulation to Treat Refractory Overactive Bladder

University of California Irvine (UCI)

Status: Completed

Conditions: Overactive Bladder

Treatments: Other: Retrospective chart review

Study type: Observational

Funder types: Other

Identifiers

NCT01047046

2008-6162

Details and patient eligibility

About

This study is a retrospective chart review including all patients who received surgical placement of a SNM device with Dr. Noblett from 2001 to the present.

Full description

The following data will be collected from patient charts: age at time of surgery, gravidity/parity, body mass index, pre-existing medical conditions/surgical history, current medications, menopausal status, form and severity of OAB symptoms, other previously or currently used interventions, method of SNM device placement, observed motor/sensory response, percent improvement of symptoms, follow-up OAB symptoms, frequency of InterStim settings adjustments, adverse events, significant changes in health, and incidence/reason for drop out.

Enrollment: 88 patients

Sex: Female

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Female patients with symptoms of OAB, namely urge incontinence and urgency-frequency.
• Ages 18 and older.

Exclusion criteria

• Any patient who received surgical placement of an SNM device to treat non-obstructive urinary retention, or the symptoms of an underlying neurologic pathology, such as Parkinson's or Multiple Sclerosis.

Trial design

88 participants in 1 patient group

SNM device placement

Description:

Patients who have undergone a placement of a SNM device to treat refractory OAB. A retrospective chart review will be performed on all patients who underwent a one or two-stage placement of an SNM device, which includes an implantable pulse generator (IPG), for refractory urge incontinence and urgency frequency symptoms. The patients will be those of Dr. Karen Noblett, having their device placed after 2001.

Treatment:

Other: Retrospective chart review