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Combined Effects of Acute Sleep Restriction and Moderate Acceleration (+Gz) on Physiological and Behavioral Responses to High Mental Workload (CogPhyAero)

D

Direction Centrale du Service de Santé des Armées

Status

Enrolling

Conditions

Sleep Deprivation

Treatments

Other: Partial sleep deprivation

Study type

Observational

Funder types

Other

Identifiers

NCT06017882
2023PBMD06
2023-A01101-44 (Other Identifier)

Details and patient eligibility

About

Fighter pilots have to perform tasks requiring high mental workload during moderate-intensity acceleration phases (2 to 3G) that can last several minutes. When these accelerations are performed in the body axis (+Gz), they induce a redistribution of blood flow in the lower limbs associated with a decrease in cerebral blood flow, partially compensated by activation of the sympathetic nervous system (baroreflex).

The main hypothesis is that the effects of these prolonged accelerations, even of moderate intensity (<+4Gz), could impair pilots' ability to perform complex cognitive tasks, with potential consequences for flight safety and mission conduct.

Moreover, flight missions are often performed after sleep debt, which is known to induce cardiovascular responses, sympathetic nervous system activation and impaired mental performance.

The secondary hypothesis is that sleep debt (3h of time spent in bed) may increase the impairment of cognitive performance during prolonged acceleration.

Enrollment

28 estimated patients

Sex

All

Ages

18 to 45 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Healthy subject (male or female);
  • Tobacco consumption < 5 cigarettes per day or nicotine-free vapour;
  • Regular physical activity (between 1 and 8 hours per week);
  • Affiliated or entitled to a social security scheme;
  • Having given their consent.

Exclusion criteria

  • Presenting an active medical pathology or a history <6 months (cardiological, renal, hepatic, cutaneous, neurological, psychiatric...), or a significant deviation from normal values observed during questioning, clinical examination or electrocardiogram (ECG);
  • BMI > 30 (cardiovascular risk factor);
  • Have a medical contraindication to sporting activities;
  • Taking a medical treatment;
  • Habitual sleep duration < 6 hours;
  • Presenting a sleep disorder confirmed by questionnaire (Pittsburgh Sleep Quality Index Questionnaire > 5);
  • Pregnant or breastfeeding
  • Not covered by a health insurance plan;

Trial design

28 participants in 4 patient groups

Group A : Usual sleep *2 ; Deprivation *2
Description:
V1->V3 id. V4 : Usual sleep and test series (easy; difficult; difficult) V5 : Usual sleep and test series (difficult; easy; easy) V6 : Sleep deprivation and test series (easy; easy; difficult) V7 : Sleep deprivation and test series (difficult; difficult; easy)
Treatment:
Other: Partial sleep deprivation
Group B : Usual sleep ; Deprivation; Deprivation ; Usual sleep
Description:
V1->V3 id. V4 : Usual sleep and test series ( difficult; difficult ; easy) V5 : Sleep deprivation and test series (easy; difficult; difficult) V6 : Sleep deprivation and test series (difficult; easy; easy) V7 : Usual sleep and test series (easy ; easy ; difficult)
Treatment:
Other: Partial sleep deprivation
Group C : Deprivation; Usual sleep ; Deprivation ; Usual sleep
Description:
V1->V3 id. V4 : Sleep deprivation and test series (easy; easy; difficult) V5 : Usual sleep and test series (difficult; difficult; easy) V6 : Sleep deprivation and test series (easy; difficult; difficult) V7 : Usual and test series (difficult; easy; easy)
Treatment:
Other: Partial sleep deprivation
Group D : Deprivation ; Deprivation ; Usual sleep ; Usual sleep
Description:
V1->V3 id. V4 : Sleep deprivation and test series (difficult; easy; easy) V5 : Sleep deprivation and test series (easy; difficult; easy) V6 : Usual sleep and test series ( difficult; easy ; easy) V7 : Usual sleep and test series (easy ; difficult; difficult)
Treatment:
Other: Partial sleep deprivation

Trial contacts and locations

1

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Central trial contact

Sauvet

Data sourced from clinicaltrials.gov

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