Combined Effects of Alternate Nostril Breathing and Aerobic Interval Training on Blood Pressure and Heart Rate Products in Patients With Hypertension

Foundation University Islamabad

Status: Enrolling

Conditions: Hypertension (HTN)

Treatments: Other: interventional group A; Other: Experimental Group

Study type: Interventional

Funder types: Other

Identifiers

NCT07177989

FUI/CTR/2025/92

Details and patient eligibility

About

Hypertension (HTN) is the foremost preventable risk factor for cardiovascular disease (CVD) and all-cause mortality, contributing to over 7 million deaths annually within the nearly 17 million attributed to CVD. Effective management through lifestyle modifications, including aerobic exercises specifically interval training presents a promising avenue for blood pressure regulation by promoting vasodilation and regulating the autonomic nervous system. Likewise, alternate nostril breathing has demonstrated efficacy in lowering blood pressure by optimizing oxygenation and improving endothelial function but their combined effect on BP measures is yet to be determined. Hence this study aims to determine the combined effects of aerobic interval training with and without alternate nostril breathing on blood pressure, rate pressure product and quality of life in patients with hypertension.

Enrollment: 36 estimated patients

Sex: All

Ages: 25 to 50 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adults aged 25- 50 years -males and females
• Patients diagnosed with stage 1 hypertension 130 - 139 / 80 - 89 mmHg and stage 2 hypertension, BP level ≥140/90 mmHg. according to AHA/ACC 2017 Guidelines-Individuals who are able to understand and follow the instructions for exercise

Exclusion criteria

• Diagnosed with any current infections
• subjects with diagnosed musculoskeletal or neurological conditions which hinder participation in physical activity program
• Active Smokers
• Those with any contraindication to exercise testing or training.
• Pregnant females

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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36 participants in 2 patient groups

Interventional group (Group B)

Experimental group

Description:

Patients in this group will perform alternative nostril breathing along with aerobic interval training. A protocol of total 5 weeks. Three sessions per week on alternate days will be done under the supervision of physiotherapist. All outcome measurements would be performed first at baseline and terminal after the 5 weeks intervention period

Treatment:

Other: Experimental Group

Interventional group (Group A)

Active Comparator group

Description:

Patients in tis group will perform aerobic interval training. A protocol of total 5 weeks. Three sessions per week on alternate days will be done under the supervision of physiotherapist. All outcome measurements would be performed first at baseline and terminal after the 5 weeks intervention period

Treatment:

Other: interventional group A