Combined Effects of Isometric Wall Squats and High Intensity Interval Training on Rate Pressure Product in Normotensive and Pre-hypertensive Sedentary Adults

Foundation University Islamabad

Status: Active, not recruiting

Conditions: Pre Hypertension

Treatments: Procedure: High Intensity Interval Training (HIIT); Procedure: Isometric Wall Squat

Study type: Interventional

Funder types: Other

Identifiers

NCT06610006

FUI/CTR/2024/34

Details and patient eligibility

About

Hypertension is leading yet preventable risk factor for cardiovascular disease and all-cause mortality worldwide. Prehypertension identifies those at high risk of developing HTN, prompting intervention to prevent or delay the onset of the disease. High intensity interval training (HIIT) is a time efficient mode of training with established benefits, while Isometric wall squats (IWS) also provide a range of proven benefits and advantages, but their combined effect on BP measures is yet to be determined.Hence the objective of this study is to compare the effects of isometric wall squats along with high intensity interval training versus high intensity interval training alone on rate pressure product, SBP and DBP, heart rate and anthropometric measures in normotensive and pre-hypertensive sedentary adults

Full description

Pre-Hypertension is not a disease itself rather it categorizes those who are at the risk of developing hypertension in future. By targeting pre-hypertensive and normotensive individuals we are focusing on preventive measures, potentially reducing incidence of HTN and cardiovascular conditions in future. If found effective, this study can help in providing training protocols while also decreasing the risk of hypertension in future.A total of 15 sessions of high intensity interval training alone in one group and combination of high intensity interval and isometric wall squat in other group, for thrice a week on alternative days for 5 consecutive weeks will be given.

Enrollment: 44 estimated patients

Sex: All

Ages: 18 to 45 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• Both male and female adults aged 18-45 years.
• Participants lying in Low PA (inactive) category on basis of IPAQ.
• Pre-hypertensive adults:
• SBP- 120 mmHg or more and <140 mmHg
• DBP of 80 mmHg or more and < 90 mmHg.
• Normotensive adults: SBP < 120 mmHg and DBP < 80 mmHg. Exclusion Criteria
• Diagnosed with any current infections.
• Subjects with any diagnosed cardiovascular or respiratory conditions.
• Subjects with diagnosed musculoskeletal or neurological conditions which hinder participation in physical activity program.
• Active Smokers
• Those with any contraindication to exercise testing or training.
• Pregnant females

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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44 participants in 2 patient groups

High Intensity Interval Training

Active Comparator group

Description:

Participants will begin with warm-up exercises for 5-7 mins before the session. Then they will begin high intensity interval training on treadmill with moderate intensity (40-60%HRR) in week 1 to achieve the baseline fitness level and from week 2 to 5 they will progress to high intensity with setting the lower target HR 40-60%HRR and upper target HR 80-85%HRR with 1:4 work to rest ratio followed by 5-7 min of cool-down period.A total of 15 sessions for thrice a week on alternative days for 5 consecutive weeks will be given

Treatment:

Procedure: High Intensity Interval Training (HIIT)

High Intensity Interval Training (HIIT) and Isometric Wall Squat

Experimental group

Description:

High intensity interval training on treadmill with moderate intensity (40-60%HRR) in week 1 to achieve the baseline fitness level and from week 2 to 5 they will progress to high intensity with setting the lower target HR 40-60%HRR and upper target HR 80-85%HRR with 1:4 work to rest ratio. For isometric wall squat, each training session will be composed of 4 × 2-min bouts of IWS followed by 2-min rest periods At the end of each bout, participants will be given an RPE score. This score will then be compared to a target RPE value and zone for each bout, There will be total 15 sessions thrice a week for 5 weeks.

Treatment:

Procedure: Isometric Wall Squat

Procedure: High Intensity Interval Training (HIIT)