Combined Intense Pulsed Light (IPL) With Fractional Erbium:YAG Laser Ablation in Scar Prevention

Hallym University Kangnam Sacred Heart Hospital

Status: Unknown

Conditions: Erbium-yttrium Aluminum Garnet Laser; Intense Pulsed Light; Scar Prevention

Treatments: Device: Intense pulse light; Device: fractional Er:YAG laser

Study type: Interventional

Funder types: Other

Identifiers

NCT04722705

2019-11-007

Details and patient eligibility

About

The scar site was divided into 3 sites; combined IPL/fractional Er:YAG laser treatment site, fractional Er:YAG laser treatment site and untreated control site. At baseline, three lesions were randomized to IPL / fractional Er:YAG laser combination therapy site, fractional Er:YAG laser treatment alone site, and untreated control site. The laser treatment was conducted total three sessions, immediately at suture removal (baseline), 4 weeks after suture removal and 8 weeks after suture removal. The evaluation of scar site was conducted 3 months later after last treatment (20 weeks after suture removal).

Enrollment: 30 estimated patients

Sex: All

Ages: 20+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Clinical diagnosis of postoperative scars on the abdomen
• scars were symmetrical shaped in a line of 3cm or more

Exclusion criteria

• uncontrolled systemic or chronic disease
• hypersensitive to the ingredients
• a history of other laser treatments within the past 6 months
• pregnancy
• lactation
• Recent sun exposure

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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30 participants in 3 patient groups

combined IPL/fractional Er:YAG laser treatment site

Experimental group

Description:

At baseline, three lesions were randomized to IPL / fractional Er:YAG laser combination therapy site. Topical anesthetic cream was applied to the scar 30 minutes before laser treatment. The same dermatologist performed all laser treatments including IPL and 2,940 nm Er:YAG fractional laser. The face was cooled after treatment with gauze soaked in ice water. The laser treatment was conducted total three sessions, immediately at suture removal, 4 weeks after suture removal and 8 weeks after suture removal. The evaluation of scar site was conducted 3 months later after last treatment.

Treatment:

Device: fractional Er:YAG laser

Device: Intense pulse light

fractional Er:YAG laser treatment alone site

Active Comparator group

Description:

At baseline, three lesions were randomized to fractional Er:YAG laser combination therapy site. Topical anesthetic cream was applied to the scar 30 minutes before laser treatment. The same dermatologist performed 2,940 nm Er:YAG fractional laser. The face was cooled after treatment with gauze soaked in ice water. The laser treatment was conducted total three sessions, immediately at suture removal, 4 weeks after suture removal and 8 weeks after suture removal. The evaluation of scar site was conducted 3 months later after last treatment.

Treatment:

Device: fractional Er:YAG laser

untreated control site

No Intervention group

Description:

At baseline, three lesions were randomized to untreated control site. Topical anesthetic cream was applied to the scar 30 minutes before laser treatment. The evaluation of scar site was conducted 3 months later after last treatment.