Combined Lumbar Erector Spinae Plane Block and Pericapsular Nerve Group Block in Patients Undergoing Hip Surgeries

Menoufia University

Status and phase: Completed; Phase 4

Conditions: Lumbar Erector Spinae Plane Block; Pericapsular Nerve Group Block (PENG Block)

Treatments: Drug: Postoperative conventional analgesia in form of Acetaminophen; Procedure: Ultrasound guided L-ESPB and PENG block using Bupivacaine

Study type: Interventional

Funder types: Other

Identifiers

NCT05930171

Lumbar ESPB and PENG block

Details and patient eligibility

About

The investigators are going to evaluate the postoperative analgesic efficacy of combined LESPB and PENG block after hip surgeries.

Full description

Hip surgeries are very common surgeries and has high postoperative pain potential. There are different ways to execute postoperative analgesia and each of them has advantages and disadvantages. As the patients submitted to this procedure are usually older and with multiple comorbidities, analgesia options with better profile of adverse effects should be preferred. Peripheral nerve block with long-acting local anesthetics is very suitable in this situation, in comparison with systemic or neuraxial opioids.

Pain control after total hip arthroplasty (THA) can be challenging because of complex innervation of the hip joint from both the lumbar and sacral nerve plexus. pain was the cause of 12% of unplanned hospital patient admissions, 60% of these patients were admitted for orthopedic concerns. The consequences of severe postoperative pain are prolonged hospital stay, increase hospital readmission, precipitation in the use of opioids with subsequent increase in postoperative nausea and vomiting, and overall low patient satisfaction. Furthermore, postoperative pain can seriously impact the physical and mental health of the patient and lead to secondary complications such as nausea, vomiting, slowed bowel movements, muscle spasms, thrombosis, cardiopulmonary complications and delayed recovery of organ functions.

The hip joint is innervated by the articular branches of multiple nerves that emerge from the lumbosacral plexus (L2-S1). The nerve supply to a specific region of the joint typically corresponds to the innervation of the muscle that crosses it :-

• The femoral nerve innervates the anterior aspect
• The obturator nerve supplies the inferior aspect
• The superior gluteal nerve supplies the superior aspect
• The nerve to the quadratus femoris innervates the posterior aspect.

Hip joint capsular innervation was found to consistently involve the femoral and obturator nerves, which supply the anterior capsule, and the nerve to the quadratus femoris, which supplies the posterior capsule.

Lumbar erector spinae plane block (LESPB) local anesthetics spread to lumbar paravertebral space and lumbar nerve roots, reaching the nerves responsible for the innervation of the hip joint lumbar plexus nerves - femoral, obturator and lateral femoral cutaneous nerves - providing analgesia for hip surgery. LESPB can be a block easier to perform than other options for hip surgery analgesia, such as posterior lumbar plexus.

(L-ESPB) is an effective analgesic technique after hip surgeries. However, an insufficient sensorial blockade of the medial part of the thigh which is innervated by the obturator nerve.

The pericapsular nerve group (PENG) block is an ultrasound-guided approach, first described by Giron-Arango et al. for the blockade of the articular branches of the femoral, obturator and accessory obturator nerves that provide sensory innervation to the anterior hip capsule. It has been successfully used as an alternative regional anaesthesia technique for the management of acute pain after hip fracture, but its applications are expanding, suggesting a potential role for analgesia after elective hip surgery.

After all the investigators hypothesize that combination of LESPB and PENG block can be more effective in pain control after hip surgeries.

Enrollment: 24 patients

Sex: All

Ages: 18 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients aged 18-70 years old
• American Society of Anesthesiologists (ASA) class I to III
• Both sex
• Scheduled for hip surgery.

Exclusion criteria

• Refusal to participate
• Allergy to any of the study drugs
• Bleeding disorder
• Localized infection
• Neurological disease
• Renal impairment
• Psychological disorders
• Opioid dependent
• Intellectual disability (patients unable to express pain with visual analogue)
• Morbid obesity.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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24 participants in 2 patient groups

Group A: L-ESPB and PENG

Active Comparator group

Description:

receiving after end of hip surgery (PENG) block first and (LESPB) at lumber 4 vertebrae level

Treatment:

Procedure: Ultrasound guided L-ESPB and PENG block using Bupivacaine

Group B: conventional analgesia

Active Comparator group

Description:

receiving postoperative conventional analgesia in form of acetaminophen 15 mg/kg/6hrs

Treatment:

Drug: Postoperative conventional analgesia in form of Acetaminophen