Combined tDCS and TMS on Subjective Tinnitus and Combined Depression

Seoul National University

Status: Completed

Conditions: Tinnitus; Depression

Treatments: Device: transcranial direct current stimulation (tDCS) and transcranial magnetic stimulation (TMS)

Study type: Interventional

Funder types: Other

Identifiers

NCT04262050

B-1607/355-004

Details and patient eligibility

About

The investigators combined transcranial direct current stimulation (tDCS) and transcranial magnetic stimulation (TMS) to increase the effective response of a single session of neuromodulation in subjective tinnitus.

Full description

To treat motor and psychiatric disorders, transcranial direct current stimulation (tDCS) and transcranial magnetic stimulation (TMS) are world-widely in use in clinics. The investigators combined these two types of neuromodulation techniques to increase the effective response of a single session of neuromodulation in subjective tinnitus. Experimental groups with 80 tinnitus subjects consisted of four different treatment groups which are tDCS, tDCS with sham TMS, tDCS-TMS and TMS group. Subjects were given 1.5milliampere (mA) tDCS on the bi-frontal area and TMS stimulated contralateral single side of the temporoparietal cortex with 200 pulses at 1herz (Hz) stimulation.

Enrollment: 80 patients

Sex: All

Ages: 19 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Research volunteers who agreed to participate in the clinical trial were gathered from the tinnitus clinic of the Department of Otorhinolaryngology Head-and-Neck Surgery, Seoul National University Bundang Hospital

Exclusion criteria

• psychoactive drug user
• implanted material
• pacemaker user

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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80 participants in 4 patient groups

TMS + tDCS group

Experimental group

Treatment:

Device: transcranial direct current stimulation (tDCS) and transcranial magnetic stimulation (TMS)

sham TMS + tDCS group

Experimental group

Treatment:

Device: transcranial direct current stimulation (tDCS) and transcranial magnetic stimulation (TMS)

tDCS group

Experimental group

Treatment:

Device: transcranial direct current stimulation (tDCS) and transcranial magnetic stimulation (TMS)

TMS group

Experimental group

Treatment:

Device: transcranial direct current stimulation (tDCS) and transcranial magnetic stimulation (TMS)