Combined Use of Machine Learning and Metabolomics to Improve the Diagnosis and Management of Hyperandrogenism (HYPERMETABO)

Assistance Publique - Hôpitaux de Paris

Status: Not yet enrolling

Conditions: Hyperandrogenism

Treatments: Other: data collection

Study type: Observational

Funder types: Other

Identifiers

NCT07253454

APHP251139

Details and patient eligibility

About

Hyperandrogenism is a common reason for consultation, the causes of which can range from common conditions (PCOS) to rarer conditions with major genetic implications (NC21OHD). It is characterized by elevated levels of circulating androgens, mainly testosterone. This excess of androgens usually manifests clinically as increased male-pattern hair growth and, less specifically, acne and alopecia. Its prevalence is estimated at between 6 and 12% in women of reproductive age, and its incidence is increasing.

It is also responsible for infertility. As a reminder, infertility is a major public health issue and affects more and more couples around the world.

The investigators therefore wish to develop innovative tools to improve the diagnosis and management of hyperandrogenism

Full description

Hyperandrogenism is a common reason for consultation, the causes of which can range from common conditions (PCOS) to rarer conditions with major genetic implications (NC21OHD). It is characterized by elevated levels of circulating androgens, mainly testosterone. This excess of androgens usually manifests clinically as increased male-pattern hair growth and, less specifically, acne and alopecia. Its prevalence is estimated at between 6 and 12% in women of reproductive age, and its incidence is increasing.

It is also responsible for infertility. As a reminder, infertility is a major public health issue and affects more and more couples around the world.

The investigators therefore wish to develop innovative tools to improve the diagnosis and management of hyperandrogenism

Enrollment: 800 estimated patients

Sex: Female

Ages: 16 to 45 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients of childbearing age (16 to 45 years old)
• Suffering from hyperandrogenism
• Established etiological diagnosis with elimination of differential diagnoses
• Informed and not opposed to the collection of their data for the purposes of the study

Exclusion criteria

• Pregnancy
• Patients under legal protection measures

Trial design

800 participants in 1 patient group

principal group

Treatment:

Other: data collection