Combining Chinese Medicine and Nutrition to Enhance Weight Loss After Bariatric Surgery

China-Japan Friendship Hospital

Status: Enrolling

Conditions: Traditional Chinese Medicine Treatment; Weight Change

Treatments: Other: Diet and meal replacements; Drug: Spleen Invigorating and Weight Reducing Decoction

Study type: Interventional

Funder types: Other

Identifiers

NCT06419764

CCMNEWLABS

Details and patient eligibility

About

This study aims to investigate the effects of Chinese herbal granule preparations on improving gastrointestinal symptoms in patients after bariatric surgery. It seeks to establish a novel treatment model that combines bariatric surgery with traditional Chinese medicine, providing clinical practice with additional evidence-based medical support.

Enrollment: 120 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. BMI ≥ 27.5 kg/m²;
2. Undergoing metabolic bariatric surgery;
3. Traditional Chinese Medicine syndrome differentiation classified as Spleen Deficiency and Excess Dampness syndrome.

Exclusion criteria

1. Contraindications for metabolic bariatric surgery;
2. Type 1 diabetes;
3. Complicated by other significant systemic diseases, such as severe liver and kidney diseases, malignant tumors, psychiatric disorders, etc;
4. Concurrent use of other medications or treatments that may affect body weight, such as metformin, semaglutide, endoscopic interventions, etc;
5. Pregnant or lactating women.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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120 participants in 2 patient groups

nutrition intervention group

Active Comparator group

Description:

Postoperative patients are routinely provided with meal replacement recommendations and dietary plans.

Treatment:

Other: Diet and meal replacements

Traditional Chinese Medicine combined with nutritional intervention

Experimental group

Description:

Chinese herbal treatment is given on the basis of routine dietary intervention.

Treatment:

Other: Diet and meal replacements

Drug: Spleen Invigorating and Weight Reducing Decoction