Combining Emotion Regulation and Mindfulness Skills for Preventing Depression Relapse

F

Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau

Status

Completed

Conditions

Major Depressive Disorder

Treatments

Behavioral: Emotion Regulation and Mindfulness skills

Study type

Interventional

Funder types

Other

Identifiers

NCT02747134
EC/07/178/2678

Details and patient eligibility

About

In the present study researchers aim to investigate the effectiveness of an intervention combining emotion regulation and mindfulness skills in a single 10-week program. A total of 75 individuals with major depressive disorder (MDD) diagnosis in complete or partial remission participated in this randomized controlled trial (RCT) comparing an intervention including emotion regulation and mindfulness skills (ER+M) with a psychoeducative program. After treatment, participants were followed for a 1-year period. Researchers results indicate that ER+M was not more effective than the treatment used with the control group in preventing depression relapse. Participants allocated to the ER+M group showed a significant decrease on global psychiatric symptoms, whereas those in the control group did not. Further studies are needed in order to better determine the combined effects of mindfulness and behavioral activation.

Enrollment

75 patients

Sex

All

Ages

18 to 75 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • age between 18 and 75 years
  • having a former MDD diagnosis in complete or partial remission at the time of the study as indicated by the major depressive section of the Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I) and scores below 17 on the Hamilton Depression Rating Scale (HSRD)
  • having the last major depressive episode between 18 and 2 months prior to the study
  • having at least two previous depressive episodes
  • patients could continue pharmacological treatment on condition that it remained stable for at least the last two months before entering the study.

Exclusion criteria

  • DSM-IV-TR criteria for current MDD or any other affective disorder
  • DSM-IV-TR criteria for alcohol or drug dependence, schizophrenia or psychotic disorders
  • DSM-IV-TR criteria for personality disorders; severe physical conditions such as organic brain syndrome or neurological disease; mental retardation or cognitive impairments
  • having received any psychotherapy including cognitive-behavioral therapy in the past
  • changes in the pharmacological treatment during the study.

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Single Blind

75 participants in 2 patient groups

Emotion Regulation and Mindfulness skills
Experimental group
Description:
A 10 week intervention including emotion regulation and mindfulness skills from dialectical behavioral therapy (DBT) was delivered.
Treatment:
Behavioral: Emotion Regulation and Mindfulness skills
Psychoeducation
Active Comparator group
Description:
Psychoeducation consisted of 5 session in which basic information about depressive symptoms and how to prevent depression relapse was given.
Treatment:
Behavioral: Emotion Regulation and Mindfulness skills

Trial contacts and locations

0

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Data sourced from clinicaltrials.gov

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