Combining Motor Imagery and Tendon Vibration on the Effectiveness of Motor Imagery (IMVT)

Centre Hospitalier Universitaire de Saint Etienne

Status: Not yet enrolling

Conditions: Healthy Volunteer

Treatments: Other: Kinesthetic motor imagery (kMI); Device: Tendon vibration (TV)

Study type: Interventional

Funder types: Other

Identifiers

NCT06845176

24CH250

2024-A02856-41 (Other Identifier)

Details and patient eligibility

About

Kinesthetic motor imagery (kMI) involves imagining the sensations of movement, activating brain regions similar to actual movement execution. It is widely used to maintain or restore motor functions, particularly in rehabilitation. Tendon vibration (TV), which stimulates proprioceptive receptors can also enhance corticospinal excitability and promote neuroplasticity. This project investigates the coupling of kMI and TV through three modalities: simultaneous application, TV application between kMI trials, or pre-application of TV to precondition the nervous system before kMI trials. The effectiveness and quality of kMI will be assessed by corticospinal excitability measurements using transcranial magnetic stimulation and EEG measures. Conducting this study in healthy participants will inform the development of optimized clinical interventions for immobilized or mobility-reduced patients.

Enrollment: 33 estimated patients

Sex: All

Ages: 18 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Men or women aged 18 to 50 years.
• Affiliated with or beneficiaries of a social security system.
• Provided written informed consent freely after being informed of the study's purpose, procedures, and potential risks.

Exclusion criteria

• History of pathology or surgery affecting upper limb motor function within 6 months prior to the study.
• Chronic neurological, motor, or psychiatric disorders.
• Use of neuroactive substances likely to alter corticospinal excitability (e.g., hypnotics, antiepileptics, psychotropics, muscle relaxants) during the study period.
• Contraindications to transcranial magnetic stimulation
• Simultaneous participation in another interventional study or participation in such a study within 30 days prior to this study.

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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33 participants in 3 patient groups

Simultaneous application of TV and kMI

Experimental group

Description:

Simultaneous application of Tendon Vibration and Kinesthesic Motor Imagery

Treatment:

Device: Tendon vibration (TV)

Other: Kinesthetic motor imagery (kMI)

TV application between kMI trials

Experimental group

Description:

Tendon Vibration application between Kinesthesic Motor Imagery

Treatment:

Device: Tendon vibration (TV)

Other: Kinesthetic motor imagery (kMI)

TV as a pre-conditionning for kMI

Experimental group

Description:

Tendon Vibration application as a pre-conditionning for Kinesthesic Motor Imagery

Treatment:

Device: Tendon vibration (TV)

Other: Kinesthetic motor imagery (kMI)