Combining Nutrition Supplementation With an Exercise Program in Elderly Malnourished Frail Patients After Hospital Stay

University Department of Geriatric Medicine FELIX PLATTER

Status

Unknown

Conditions

Malnutrition; Protein

Frailty

Sarcopenia

Treatments

Combination Product: Intervention consisting of a multicomponent exercise program combined with an oral nutritional supplement

Study type

Interventional

Funder types

Other

Identifiers

NCT05325697

2021-01058

Details and patient eligibility

About

The objective of this study is to investigate the feasibility of a combined nutritional and home-based exercise intervention in elderly, malnourished, frail patients after hospital discharge.

Adherence to exercise program, adherence to oral nutrition supplement, potential inhibiting factors to follow exercise program, changes in nutritional status, muscle mass and function, quality of life are outcome factors.

The intervention consists of 12 weeks with a physical exercise program (vivifrail) and oral nutritional supplementation (Moltein Plus).

The investigators hypothesize that 12 weeks of a combined nutritional and home-based multicomponent exercise program is feasible for frail elderly patients after hospital discharge, meaning that ≥70% of the exercise sessions will be completed and oral supplements will be consumed by the participants.

Enrollment

15 estimated patients

Sex

All

Ages

65+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Age ≥ 65
Malnutrition: Nutrition Risk Screening ≥3
Frail/pre-frail status according Fried Frailty Phenotype: 1-2 criteria present = pre frail, > 2 criteria present = frail
Frailty status according to SPPB: A: 0-3 points = disabled, B (B+): 4-6 points = frail (at risk of falls), C (C+): 7-10 points = pre-frail (at risk of falls), D: 10-12 points = robust.
Ability to sit
Consent to participate in the study
Ability to follow the instructions of the vivifrail program
Prescription for use of an ONS

Exclusion criteria

Severe acute cardiovascular issues: eg. unstable angina pectoris, uncontrolled arrhythmia, uncontrolled arterial hypertension or unstable cardiovascular disease or other unstable medical condition.
Persisting oedema and/or ascites
Contraindication for the protein-rich ONS (e.g. cow's milk allergy, end stage renal disease without renal replacement therapy) or dysphagia for liquids
non-removable plasters or bandages at feet or hands aggravating body impedance analysis (BIA), implanted defibrillation device
Parenteral/tube feeding
No access to telephone or severe hearing loss
Terminal illness
Hospitalized due to pulmonary thromboembolism
Considerable cognitive impairment: Mini-mental score < 18 or advice of healthcare professionals against inclusion due to cognitive or psychological reasons.