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Communicating Risk Information for Obesity

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Boston University

Status

Completed

Conditions

Obesity

Treatments

Behavioral: Lifestyle
Genetic: Genetic

Study type

Interventional

Funder types

Other
NIH

Identifiers

NCT01355224
1R21HG006073-01 (U.S. NIH Grant/Contract)
CW-R21

Details and patient eligibility

About

This study will examine the impact of providing genetic risk information for obesity on people's attitudes and beliefs about obesity, health behaviors and weight outcomes. Specifically, this study will examine the feasibility of using genetic information to motivate efforts to reduce obesity among individuals recruited to the Coriell Personalized Medicine Collaborative (CPMC), see below for description of CPMC.

Full description

The investigators will conduct a randomized controlled feasibility trial to examine the short-term impact of personalized risk feedback for obesity. This study is uniquely situated to provide important data on how individuals interpret various sources of risk information and how they arrive at an overall perception of risk for a condition. Taken altogether, study findings will be used to serve as an overall model for future intervention efforts to effectively communicate obesity risk information with the goal of improving weight management and overall population health.

CPMC-The CPMC is an ongoing evidence-based longitudinal research study designed to determine the utility of using personal genome information in health management and clinical decision-making. They collect saliva samples, perform genetic analysis and provide genetic risk feedback for several disease conditions including coronary artery disease and type 2 diabetes. The present study will build upon the existing genetic testing and web feedback infrastructure at Coriell to conduct behavioral science research to address critical public health questions.

Enrollment

798 patients

Sex

All

Ages

18+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Must be age 18 or older, active enrollees in the CPMC trial, and able to read and write in English.

Exclusion criteria

Individuals that do not meet the inclusion criteria.

Trial design

Primary purpose

Prevention

Allocation

Randomized

Interventional model

Factorial Assignment

Masking

Double Blind

798 participants in 4 patient groups

No risk feedback
No Intervention group
Description:
No obesity risk information given (control)
Genetic risk feedback
Experimental group
Description:
Only personal genetic risk information provided
Treatment:
Genetic: Genetic
Lifestyle risk feedback
Experimental group
Description:
Only personal lifestyle risk information provided
Treatment:
Behavioral: Lifestyle
Both genetic or lifestyle risk feedback
Experimental group
Description:
Personal genetic and lifestyle information provided
Treatment:
Genetic: Genetic
Behavioral: Lifestyle

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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