Communication Strategies to Increase HPV Vaccination Intention

University of Pennsylvania

Status: Enrolling

Conditions: Vaccine Hesitancy; Communication; Papilloma Viral Infection

Treatments: Behavioral: Messages

Study type: Interventional

Funder types: Other

Identifiers

NCT06784960

856892

Details and patient eligibility

About

This research aims to identify communication strategies to improve the uptake of vaccines using an experimental design, focusing on the Human Papillomavirus (HPV) vaccine, which is highly effective in preventing HPV-related cancers. However, low HPV vaccination rates among adults remain a significant public health challenge. Although randomized controlled trials (RCTs) have demonstrated that interventions can increase vaccine uptake in children, few RCTs have been conducted on adults. To address this gap, a multidisciplinary investigative team with expertise in communication, medicine, nursing, and behavior-change intervention research, and a history of extensive collaboration, will conduct a survey experiment on a national sample of over 3,689 adults to identify the most promising theory-based messages to strengthen HPV vaccine intentions.

Enrollment: 3,689 estimated patients

Sex: All

Ages: 18 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• 18-45 years old

Exclusion criteria

• Under 18 and over 45 years old
• Received HPV vaccine or unsure about receipt

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

---

3,689 participants in 6 patient groups

Theory-Based Message Condition 1

Experimental group

Treatment:

Behavioral: Messages

Theory-Based Message Condition 2

Experimental group

Treatment:

Behavioral: Messages

Theory-Based Message Condition 3

Experimental group

Treatment:

Behavioral: Messages

Theory-Based Message Condition 4

Experimental group

Treatment:

Behavioral: Messages

Theory-Based Message Condition 5

Experimental group

Treatment:

Behavioral: Messages

Theory-Based Message Condition 6

Active Comparator group

Treatment:

Behavioral: Messages