Community-based, Peer-delivered PrEP for Female Sex Workers in Rural Uganda: The Peers for PrEP (P4P) Study

University of California San Francisco (UCSF)

Status

Active, not recruiting

Conditions

HIV/AIDS

Treatments

Other: P4P intervention

Study type

Interventional

Funder types

Other

Industry

Identifiers

NCT06353295

22-38098

CO-US-412-6436 (Other Grant/Funding Number)

Details and patient eligibility

About

The overall goal of the P4P: Peers for PrEP (pre-exposure prophylaxis) study is to pilot test a peer-led and delivered intervention for biomedical HIV prevention that is tailored to women who engage in sex work in southwestern Uganda. This study will evaluate whether this intervention is feasible, acceptable, and increases uptake of biomedical prevention.

Full description

The investigators have collaborated with key stakeholders to develop a community-based, peer-led intervention to provide biomedical prevention products (e.g. pre-exposure prophylaxis [PrEP] and post-exposure prophylaxis [PEP]) for women who engage in sex work in southwestern Uganda. A single-arm pilot trial will evaluate the feasibility, acceptability, and preliminary effectiveness of the intervention. The intervention is designed to reduce stigma associated with attending clinics (via community-based delivery by peers), leverage peer support to foster adherence, and reduce barriers to prevention services (through access to PrEP, HIV self-testing, and PEP from trusted peers).

Enrollment

140 estimated patients

Sex

Female

Ages

15+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Female sex at birth
Self-identified as commercial sex worker; exchange of sex for goods or money in last 3 months; or work or live in setting associated with sex work
Age >=18 years (or mature minor >=15 years)
HIV-negative by country-standard rapid testing algorithm

Exclusion criteria