Community Based Screening for Colorectal Cancer in an Underserved High Risk Population in Nigeria

Obafemi Awolowo University Teaching Hospital

Status

Completed

Conditions

Colorectal Cancer

Treatments

Procedure: Colonoscopy

Study type

Observational

Funder types

Other

Identifiers

NCT03032874

ERC/2013/02/07

Details and patient eligibility

About

Patient age 45 year old and above who presented with rectal bleeding at three tertiary hospitals in South West Nigeria were invited for colonoscopy. The clinical information of the patients and the colonoscopy data were analyzed

Full description

Patient age 45 year old and above who presented with rectal bleeding at Obafemi Awolowo University Teaching Hospitals Complex, Ile Ife, Nigeria, University College Hospital, Ibadan, Nigeria, and University of Ilorin Teaching Hospital, Ilorin Nigeria were invited for colonoscopy. Categorical variables were compared using χ2-test or Fisher's exact test while the Kruskal-Wallis test was used for quantitative variables. Multivariate analysis was performed using logistic regression model. All statistical tests were two-sided and p-values below 0.05 were considered statistically significant. Statistical analysis was carried out using SAS 9.4 and R 3.3.1.

Enrollment

100 patients

Sex

All

Ages

45+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

must be 45-years of age or older
has rectal bleeding lasting at least one week
has had a complete colonoscopy performed

Exclusion criteria

Individuals with a personal history of inflammatory bowel disease, colorectal polyps, colorectal adenoma or CRC
Individuals with a family history of familial adenomatous polyposis syndromes or other hereditary polyposis syndromes, hereditary nonpolyposis colorectal cancer
Individuals with severe comorbidities that were contraindication to colonoscopy
Individuals who had a previous history of colectomy