Community Epidemiology and Typology of Third-generation Cephalosporins Resistant Enterobacteriaceae in Reunion Island (AB-RUN)

Centre Hospitalier Universitaire de la Réunion

Status: Unknown

Conditions: Bacterial Resistance

Treatments: Procedure: stool sample

Study type: Observational

Funder types: Other

Identifiers

NCT03226314

2015/CHU/14

Details and patient eligibility

About

In its report dated april 2014, World Health Organization confirms antibiotic resistance dissemination in all parts of the world, in hospitals and in community and worries about a possible comeback to a pre-antibiotic era during the 21st century. For the last 15 years, third-generation cephalosporins resistant enterobacteriaceae (3GCREB) prevalence is continuously increasing. Community 3GCREB prevalence has not been studied whereas several observations made in Reunion Island hospital suggest a diffusion in community. In this situation of world-wide and regional extension of bacterial resistance, the investigator offers to study bacterial resistance to antibiotic in Reunion Island community.

Full description

The investigator is focused on E. coli species exhibiting BLSE or metallo-betalactamases production that could be encountered du to the increasing level of migratory flow in Reunion Island.

Fecal sample collection will be used for further investigations on bacterial typology.

Enrollment: 500 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

Patients:

• aged over 18 years old
• admitted in emergency ward or intensive care of the university hospital of Reunion Island
• who received the patient information notice and who gave their consent
• who have a stool sample performed in the 48 hours following admission
• who understand and can read French

Exclusion criteria

Patients:

• transferred from a short-term, middle-term or long-term stay health facility
• who have a stool sample performed more than 48 hours following admission.

Trial design

500 participants in 1 patient group

stool sampled community patients

Description:

community patients entering emergency ward or intensive care unit in Reunion Island university hospital and having the stools sampled for bacterial analysis.

Treatment:

Procedure: stool sample