Community Preparedness for Outbreak Response and Readiness for Ebola Vaccination in Liberia

UL-PIRE Africa Center

Status: Not yet enrolling

Conditions: Ebola Virus Disease

Treatments: Behavioral: Community Clusters

Study type: Observational

Funder types: Other

Identifiers

NCT05888649

MISP 101054

Details and patient eligibility

About

This community-based mixed methods study intends to identify, explore, and assess the determinants of community preparedness for outbreak situations, including acceptance for Ebola vaccines.

Full description

This community-based study intends to identify, explore, and assess the determinants of community preparedness for outbreak situations and acceptance for the administration of Ebola vaccination. The investigators will conduct an anthropologically driven mixed methods study design that comprises both qualitative and quantitative research methods for the successful implementation of this community-based study. The investigators will conduct structured interviews with community members and local responders to broadly assess and understand the perspectives regarding appropriate strategies previously employed to effectively support community preparedness during outbreak response and also to broadly access and understand appropriate strategies previously employed to effectively support community acceptance for Ebola vaccines, respectively. Learning from the experiences of local voices produces globally emergent systems that are trusted, reliable and sustainable.

Enrollment: 1,500 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Adults
• Community Leaders
• Community Members
• Reside in 1 of 3 highly prevalent counties
• Participated actively in EVD outbreaks related activities
• Documented roles recognized by the Incident Management System

Exclusion criteria

• Not Adults
• Does not reside in any of the 3 highly prevalent counties
• Did not actively participate in the EVD outbreak response related activities
• Roles not documented by the Incident Management System

Trial design

1,500 participants in 4 patient groups

Cluster 1

Description:

Communities highly affected and impacted by EVD

Treatment:

Behavioral: Community Clusters

Cluster 2

Description:

Communities not highly affected and impacted by EVD

Treatment:

Behavioral: Community Clusters

Cluster 3

Description:

Communities receptive to EVD vaccination

Treatment:

Behavioral: Community Clusters

Cluster 4

Description:

Communities resistance to EVD vaccination

Treatment:

Behavioral: Community Clusters