Comparaison of 3 Protocols of Ocytocin Administration in C Section

Mongi Slim Hospital

Status

Completed

Conditions

Cesarean Section Complications

Oxytocin Adverse Reaction

Treatments

Drug: Ocytocin

Study type

Interventional

Funder types

Other

Identifiers

NCT04046510

Ocytocin in c section

Details and patient eligibility

About

This study aimed to compare 3 doses of ocytocin in bolus injection and contnious perfusion during C section. these doses determined by: high, intermediate and low doses, were administred to parturients during elective or urgent C section under spinal anesthesia

Full description

The aim was to determine the lowest efficient dose to prevent post partum hemorrage and with the lowest incidence of maternal side effects.

Enrollment

180 patients

Sex

Female

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

All adult patients scheduled for C section under spinal anesthesia, monofoetal pregnancy, full term

Exclusion criteria

necessity of general anesthesia
non conscent

Trial design

Primary purpose

Prevention

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Double Blind

180 participants in 3 patient groups

High doses

Active Comparator group

Description:

the patients of this group recieved conventionnal doses of ocytocin after foetal extraction in C section: 5IU in bolus followed by 15IU in continuous infusion

Treatment:

Drug: Ocytocin

Intermediate doses

Experimental group

Description:

the patients of this group recieved after foetal extraction in C section: 2IU in bolus followed by 10IU in continuous infusion

Treatment:

Drug: Ocytocin

Low doses

Experimental group

Description:

the patients of this group recieved after foetal extraction in C section: 2IU in bolus followed by 5 IU in continuous infusion