Comparative Analysis of Radiotherapeutic and Medical Procedures for the Prophylaxis of Heterotopic Ossifications (CONFIDENTIAL)

University of Jena

Status: Completed

Conditions: Hip Arthropathy; Heterotopic Ossification; Myositis Ossificans Traumatica, Thigh

Treatments: Radiation: Radiation; Drug: Diclofenac

Study type: Observational

Funder types: Other

Identifiers

NCT06251349

2023-3175-Daten

Details and patient eligibility

About

Aim of this study is to proof the efficacy of in Jena established prophylaxis of new bone formation aside the skeleton with irradiation and compare it with the common literature. Furthermore we want to compare irradiation treatment with the alternative prophylaxis with analgetics from the NSAID type.

Full description

Aim of this retrospective analysis is to compare the incidence of heterotopic ossification one year after total hip arthroplasty with the at our location established concept of irradiation 24h preoperative and incidence in common literature. Furthermore the comparison between irradiated patients and patients treated with NSAIDs.

Enrollment: 512 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

Patients with total hip arthroplasty performed at Eisenberg Patients with preoperative irradiation (24h pre-op) or postoperative diclofenac treatment Patients with x-ray images immediately (3-5 days postoperative) postoperative and at least 365 days postoperative

Exclusion criteria

Patients with missing follow up image

Trial design

512 participants in 2 patient groups

Intervention group with prophylactic irradiation

Description:

Patients with total hip arthroplasty and irradiation (preoperative on the day before the operation (\>24h preoperative)) Quantity: 128 Period: 01.01.2013 - 31.12.2023

Treatment:

Radiation: Radiation

Control group with prophylactic NSAID-treatment

Description:

Patients with total hip arthroplasty and diclofenac treatment Quantity: 384 Period: 01.01.2013 - 31.12.2023

Treatment:

Drug: Diclofenac