Comparative Analysis of Serum Lipid Profiles in Patients With and Without Gallstones

Services Hospital, Lahore

Status

Completed

Conditions

Gallstone

Dyslipidemias

Treatments

Diagnostic Test: Serum lipid profile

Study type

Observational

Funder types

Other

Identifiers

NCT03804775

s10

Details and patient eligibility

About

Gallbladder disease is one of the most common diseases of the gastrointestinal tract. Various studies have shown an association between gallstones and an alteration in the serum lipids. The objective of this study will be to compare serum lipid profile of gallstone patients with the controls.

Full description

This prospective cross-sectional study will be conducted in the Surgical Department of the Services Institute of Medical Sciences. A total of 50 patients will beincluded in the study after screening through the inclusion criteria. A control group of 50 inpatients with no personal or family history of gallstones will be also recruited for comparison. Results will be expressed as mean with standard deviation. Students t- test will be used to compare the data between the patients and the control groups (p<0.05 will be considered statistically significant). SPSS software, version 20 will be used for statistical analysis.

Enrollment

100 patients

Sex

All

Ages

20 to 70 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Male or female patients with the gall stone disease
Age from 20 to 70 years
Gallstones were diagnosed through the ultrasound

Exclusion criteria

Patients with acalculous gallbladder disease on ultrasound,
Patients with terminal ileal resection,
Patients with hemolytic diseases (hereditary spherocytosis, sickle cell anemia on history and CBC film),
Patients with liver cirrhosis (on abdominal ultrasound) and
Patients on antihyperlipidemic drugs