Comparative Clinical Trial of Lornoxicam to Diclofenac in Patients of Osteoarthritis of Knee Joint.

Government Medical College, Bhavnagar

Status: Completed

Conditions: Osteoarthritis of Knee Joint

Treatments: Drug: Diclofenac; Drug: Lornoxicam

Study type: Interventional

Funder types: Other

Identifiers

NCT01055470

Pharmacol no.02 /2008 Research

Details and patient eligibility

About

The purpose of this study was to compare the pain relieving action of the lornoxicam and diclofenac in patients of OA knee.

Enrollment: 40 patients

Sex: All

Ages: 25 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Newly diagnosed patient aged between 25 to 65 yrs of either gender suffering from osteoarthritis of knee according to criteria given by American College of Rheumatology
• Informed consent obtained from the patient.

Exclusion criteria

• Patients with any other systemic llness,
• Patients with pregnancy and lactation,
• Patients taking other drugs like lithium[4], digoxin, methotrexate, anticoagulants, antidiabetics, diuretics,
• Patients with H/O hypersensitivity to NSAIDs,
• Patients who had consumed any analgesics in last 1 month

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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40 participants in 2 patient groups

Diclofenac

Active Comparator group

Description:

Tab.Diclofenac 50 mg ,Orally, 12 hrly in morning and in evening after taking food for 3 months.

Treatment:

Drug: Diclofenac

Lornoxicam

Experimental group

Description:

Tab. Lornoxicam 4 mg , orally, 8 hourly after taking food in morning , in noon and evening for 3 months.

Treatment:

Drug: Lornoxicam