Comparative Effect of 3 Different Cranberry Extracts on Cystitis Related Urinary Comfort in Women

CEN Biotech

Status

Completed

Conditions

Recurrent Cystitis

Treatments

Dietary Supplement: X

Dietary Supplement: Z

Dietary Supplement: Y

Study type

Observational

Funder types

Industry

Other

Identifiers

NCT04962971

C1635

Details and patient eligibility

About

Urinary discomfort includes a set of signs such as an urgent need to urinate, high frequency of urination per day, discomfort / difficulty or burning sensation when urinating, smelly urine. This urinary discomfort represents in women 2 to 5% of the reasons for consultation (Berg, 1991) and can have various etiologies but the bacterial origin is the most frequent. Cranberries are traditionally used for urinary comfort and the prevention of urinary disorders with bacterial origin.

The study objective is to collect in real life efficacy and tolerance data from the consumption of 3 cranberry extracts in order to highlight the qualitative and quantitative characteristics of these extracts which are directly involved in the improvement of urinary discomfort or situation of recurrent cystitis symptomatic episodes in women.

Enrollment

216 patients

Sex

Female

Ages

18 to 65 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

having had at least 3 symptomatic episodes of cystitis (including 1 urinary tract infection confirmed by a doctor) during the last 12 months
whose episode had a significant impact on quality of life / urinary discomfort (ACSS Dimension QoL ≥ 2)
had a smartphone compatible with Nurstrial smartphone application (e-CRF)

Exclusion criteria

to be a pregnant or breastfeeding woman or planning to be pregnant within 6 months,
currently taking any other supplementation for urinary comfort or having taken any other cranberry-based food supplement in the past 3 months,
to be under antibiotic treatment or during the last 7 days preceding inclusion,
have urinary discomfort with a severe impact on quality of life (ACSS QoL> 7) during the last 24 hours prior to inclusion,
have an allergy known to plants of the cranberry family or to one of the components of the products.