Comparative Effectiveness Trial of Two Reminder/Recall Methods to Increase Immunization Rates in Young Children

University of Colorado Denver (CU Denver)

Status: Completed

Conditions: Immunization Rates

Treatments: Behavioral: Practice-based Recall; Behavioral: Collaborative Pop-Based R/R: Mail-Only Group; Behavioral: Collaborative Pop-Based R/R: Phone/Mail Group

Study type: Interventional

Funder types: Other; Other U.S. Federal agency

Identifiers

NCT01557621

11-1480

P01HS021138 (U.S. AHRQ Grant/Contract)

Details and patient eligibility

About

The purpose of this study is to determine if a collaborative centralized population-based reminder/recall intervention is more effective than a traditional practice-based reminder/recall intervention at increasing immunizations among young children.

Full description

The study proposed is of immense importance in directing future methodology for bringing children who have not received needed immunizations up to date. The proposed study builds on the success of a previous trial and incorporates data from providers and patients to further improve the intervention. In this study the investigators aim to increase the effectiveness, cost effectiveness, and acceptability to practices and families of population-based R/R by introducing a strong private-public collaboration and maximizing health information technologies that allow practices to interface with Colorado's Immunization Services System (CIIS). Two real-world approaches will be compared: one approach will provide primary care practices the tools to conduct recall and educational interventions. In the other approach, population-based centralized recall by the state immunization registry will be conducted in collaboration with practices. Determining which of these methods is most effective in reaching the most children and comparing the cost of each will provide data critical in guiding future national efforts to assure that children entering school are fully vaccinated. Because the trial will be conducted at the level of both urban and rural counties throughout the state and will include all types of providers, the investigators expect our findings to be nationally generalizable.

Enrollment: 68,000 patients

Sex: All

Ages: 19 months to 5 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 19-35 months at time of recall
• has an address in a specified study county listed in the state immunization registry
• child is in need of at least one immunization at time of study

Exclusion criteria

• Opted out of the Colorado Immunization Information System (CIIS)
• child is up-to-date on all immunizations

Trial design

Primary purpose: Health Services Research

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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68,000 participants in 3 patient groups

Collaborative Population-Based Recall-Phone/Mail Group

Experimental group

Description:

Collaborative Pop-Based R/R: Phone/Mail Group Private providers, local public health departments, and the state immunization registry (CIIS) collaborate to send notices to families whose children appear in need of an immunization.

Treatment:

Behavioral: Collaborative Pop-Based R/R: Phone/Mail Group

Collaborative Population-Based Recall-Mail Only Group

Experimental group

Description:

Collaborative Pop-Based R/R: Mail-Only Group Private providers, local public health departments, and the state immunization registry (CIIS) collaborate to send notices to families whose children appear in need of an immunization.

Treatment:

Behavioral: Collaborative Pop-Based R/R: Mail-Only Group

Practice-based Recall

Active Comparator group

Description:

Practice-based Recall

Treatment:

Behavioral: Practice-based Recall