Comparative Effects of Using Black Seed and Cumin Seed on BCP of Obese Grade I

Sehat Medical Complex

Status and phase: Enrolling; Phase 1

Conditions: Obese

Treatments: Dietary Supplement: Black Seed ( Nigella Sativa); Dietary Supplement: Cumin Seed (Cuminum Cyminum)

Study type: Interventional

Funder types: Other

Identifiers

NCT05770791

ZaraYameen001-23

Details and patient eligibility

About

The goal of this Randomized clinical trial is to compare effectiveness of of using black seed (Nigella sativa) and cumin seed (Cuminum cyminum) on Body composition profile of obese grade 1. The primary objective of this study is To compare effectiveness of of using black seed (Nigella sativa) and cumin seed (Cuminum cyminum) on Body composition profile of obese grade 1. Subjects will be given a consent form and after subjects read and sign the informed consent, they would be included in study according to eligibility criteria.

Full description

Obesity is a global pandemic that is associated with high morbidity and mortality. Natural herbs are commonly used for weight reduction and appetite suppression. Worldwide data based on 1698 studies has shown that the global prevalence of obesity has increased from 3.2 to 10.8% in men and from 6.4 to 14.9% in women. Meanwhile, herbal products are marketed for their weight-loss properties, such as Nigella sativa which has been used for centuries to treat rheumatoid arthritis, diabetes, and asthma; recently, the anti-obesity characteristics of N. sativa have also been indicated. The antihyperglycemic activity, inhibition of free radical formation, anti-obesity and anti-inflammatory activity of cumin seed extract have also been reported previously.

Enrollment: 55 estimated patients

Sex: All

Ages: 25 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Subject having BMI between 30 kg/m2 - 34.5 kg/m2

Exclusion criteria

• Subjects having kidney or liver problems
• Having ulcers in GIT
• Subjects having hypertension, thyroid, diabetes or cardiovascular disorders
• Pregnant and lactating mothers
• Subjects who are using hormonal or anti-obesity medications

Trial design

Primary purpose: Health Services Research

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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55 participants in 2 patient groups

Group A

Active Comparator group

Description:

Group A Obese Grade I

Treatment:

Dietary Supplement: Black Seed ( Nigella Sativa)

Group B

Active Comparator group

Description:

Group B Obese Grade I

Treatment:

Dietary Supplement: Cumin Seed (Cuminum Cyminum)