Comparative Efficacy and Safety of Benzoyl Peroxide Used in Combination With Clindamycin vs. Benzoyl Peroxide Used in Combination With Clindamycin and Doxycycline in the Treatment of Moderate Acne

Stiefel

Status and phase: Completed; Phase 4

Conditions: Acne

Treatments: Drug: Benzoyl peroxide with clindamycin; Drug: Benzoyl peroxide with clindamycin and doxycycline

Study type: Interventional

Funder types: Industry

Identifiers

NCT00837213

EVF0701

Details and patient eligibility

About

To compare the efficacy and safety of Benzoyl peroxide used in combination with clindamycin vs. Benzoyl peroxide used in combination with clindamycin and doxycycline in the treatment of moderate acne

Full description

To compare the efficacy and safety of Benzoyl peroxide used in combination with clindamycin vs. Benzoyl peroxide used in combination with clindamycin and doxycycline once daily in the treatment of moderate acne

Enrollment: 33 patients

Sex: All

Ages: 16+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Male or female subjects with acne vulgaris . Able to understand the requirements of the study and sign informed consent/HIPAA authorization forms.

Exclusion criteria

• Known hypersensitivity to any of the components of the study drugs or used of prohibited medications or any medical condition that contraindicate the subject's participation in the clinical study

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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33 participants in 2 patient groups

BPO with clindamycin foam

Active Comparator group

Description:

Benzoyl peroxide (BPO) wash with clindamycin foam

Treatment:

Drug: Benzoyl peroxide with clindamycin

BPO + clindamycin foam + doxycycline

Active Comparator group

Description:

Benzoyl peroxide (BPO) wash with clindamycin foam and doxycycline capsules

Treatment:

Drug: Benzoyl peroxide with clindamycin and doxycycline