Comparative Efficacy of Topical 1% Clotrimazole vs Oral Itraconazole in the Treatment of Pityriasis Versicolor

Combined Military Hospital Abbottabad

Status and phase: Not yet enrolling; Phase 2; Phase 1

Conditions: Pityriasis Versicolor

Treatments: Drug: Topical 1 % clotrimazole twice daily 2 weeks; Drug: Oral itraconazole 200mg daily for 5 days

Study type: Interventional

Funder types: Other

Identifiers

NCT07331792

CMH-Atd-ETH-200-Derm-25

Details and patient eligibility

About

Comparative efficacy of topical 1% clotrimazole vs oral itraconazole in the treatment of pityriasis versicolor -Randomized control trial

Enrollment: 86 estimated patients

Sex: All

Ages: 15 to 50 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age (15-50 years)
• Both genders
• Sufferers of Pityriasis versicolor ( Determined by scale , erythema and pruritus)

Exclusion criteria

• Pt with history of antifungals in last one month
• Pt on immunosuppressants or steroid therapy
• Pregnant and lactating women
• Pt with chronic medical conditions ( Diabetes and hypertension)

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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86 participants in 2 patient groups

1% Clotrimazole

Experimental group

Description:

topical 1 % clotrimazole twice daily for 2 weeks

Treatment:

Drug: Topical 1 % clotrimazole twice daily 2 weeks

Itraconazole

Experimental group

Description:

Oral itraconazole 200mg daily 5 days

Treatment:

Drug: Oral itraconazole 200mg daily for 5 days