Comparative Evaluation of the Efficacy of Intraoral Cryotherapy Versus Intracanal Cryotherapy on Postoperative Pain

Cairo University (CU)

Status: Unknown

Conditions: Postoperative Pain

Treatments: Procedure: Intracanal Cryotherapy; Procedure: Intraoral Cryotherapy

Study type: Interventional

Funder types: Other

Identifiers

NCT05041738

ENDO 3-3-5 8/9/2021

Details and patient eligibility

About

The aim of this study is to clinically compare the efficacy of intraoral cryotherapy versus intracanal cryotherapy after single visit root canal therapy in lower molars with irreversible pulpitis and symptomatic apical periodontitis

Enrollment: 68 estimated patients

Sex: All

Ages: 20 to 20 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

Systemically healthy patient (ASA I or II).

Mandibular first molar teeth with:

• Preoperative sharp pain and symptomatic apical periodontitis
• Absence or slight widening in the periodontal ligament (PDL).
• Vital response of pulp tissue to cold pulp tester (ethyl chloride spray) .
• Positive response to percussion test

Exclusion criteria

1. Medically compromised patients.
2. Pregnant women.
3. Patients reporting bruxism or clenching.
4. Patients allergic to ciprofloxacin or metronidazole.
5. Teeth associated with acute periapical abscess and/or swelling.
6. Greater than grade I mobility or pocket depth greater than 5mm.
7. Size of periapical radiolucency is greater than 8 mm.
8. No restorability: Hopeless tooth.
9. Immature teeth.
10. Radiographic evidence of external or internal root resorption vertical root fracture, perforation, calcification.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

---

68 participants in 2 patient groups

Intraoral Cryotherapy

Experimental group

Treatment:

Procedure: Intraoral Cryotherapy

Intracanal Cryotherapy

Active Comparator group

Treatment:

Procedure: Intracanal Cryotherapy