Comparative Study Between Early Vitrectomy and Observation for Spontaneous Closure of Traumatic Macular Hole

Peking University

Status

Completed

Conditions

Trauma

Macular Hole

Treatments

Procedure: vitrectomy surgery

Study type

Interventional

Funder types

Other

Identifiers

NCT01509092

PekingUTH-TMH-2011

Details and patient eligibility

About

The purpose of this study is to compare the anatomical and visual recovery of eyes with traumatic macular hole (TMH) following either early vitrectomy or 6-month observation.

Full description

Patients who received vitrectomy immediately after the injury were compared with patients who were observed for six months for spontaneously closure.The closure rate, foveal microstructure, and final visual acuity were analyzed.

Enrollment

44 patients

Sex

All

Volunteers

No Healthy Volunteers

Inclusion criteria

closed globe injury
identification of full-thickness macular hole by optical coherence tomography within one month after trauma

Exclusion criteria

open globe injury
coexistence of idiopathic macular hole
severe opaque in the visual axis caused by the injury(eg. severe cataract, severe vitreous hemorrhage)
combined injuries requiring immediate surgical intervention (eg. lens dislocation, retinal detachment, cyclodialysis)
coexistence of high myopia
coexistence of choroidal rupture or subretinal hemorrhage within the diameter of 400μm from the center of the foveola
coexistence of severe optic nerve injury (no light perception, positive afferent pupillary defect)