Comparative Study Between Porcine and Autologous Cortical Plates

Universidad Complutense de Madrid

Status: Completed

Conditions: Bone Regeneration

Treatments: Procedure: split bone block technique

Study type: Interventional

Funder types: Other

Identifiers

NCT04205591

P-15/567

Details and patient eligibility

About

The aim of this study is to evaluate the outcome of three-dimensional bone regeneration procedures using thin cortical porcine xenograft plates in combination with autogenous bone chips compared with thin autogenous cortical plates and autogenous bone chips.

Full description

Materials and methods: 16 patients referred for implant placement and with insufficient bucco-lingual (BL) alveolar bone width (<4 mm) were included in the study. Patients received autogenous cortical plates (ACP) of either porcine xenogeneic (XCP). The aforementioned groups were compared in regards to bone augmentation using General Estimating Equations (GEE) and logistic regression. Demographic data, trabecular bone density, graft site, postoperative pain, and time consuming were also analyzed

Enrollment: 16 patients

Sex: All

Ages: 18 to 68 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients were enrolled in the study on the basis of having insufficient bone height (<6mm), width (<3mm) or both, in either maxilla or mandible

Exclusion criteria

Patients with severe systemic disease (American Society of Anesthesiology III or IV) were excluded from the study.

In addition, patients who were pregnant, or patients with diseases affecting bone, such as:Paget's disease, osteomalacia, diabetes, vitamin D deficiency, alcoholism, hyperthyroidism cancer or osteoporosis as well as those on medications that might affect bone metabolism, such as bisphosphonates, corticosteroids or antiepileptic medicaments were also excluded from the study.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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16 participants in 2 patient groups

Autologous cortical plate

Active Comparator group

Description:

Thin autologous cortical plates that allow to made a rigid and resistant framework that will be filled with autogenous bone chips bone

Treatment:

Procedure: split bone block technique

Porcine cortical plate

Experimental group

Description:

Thin porcine cortical platesthat allow to made a rigid and resistant framework that will be filled with autogenous bone chips bone

Treatment:

Procedure: split bone block technique