Comparative Study of Photodynamic Therapy vs. CO2 Laser Therapy in Treatment of Actinic Keratoses

Ruhr University of Bochum

Status: Unknown

Conditions: Actinic Keratosis

Treatments: Procedure: ablative CO2 laser therapy; Procedure: photodynamic therapy

Study type: Interventional

Funder types: Other

Identifiers

NCT01481155

PDT vs. CO2

Details and patient eligibility

About

The purpose of this study is to determine whether photodynamic therapy or CO2 laser therapy is superior in the treatment of actinic keratoses with respect to efficacy and side effects.

Full description

Ablative laser therapy and photodynamic therapy are widely used and accepted therapeutic methods to treat multiple actinic keratoses, yet comparative studies are rare. The purpose of this study is to compare both treatments intraindividually with respect to treatment efficacy and side effects.

Enrollment: 21 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• men and women with clinical and histological diagnosed, symmetrical distributed actinic keratoses
• at least 2 actinic keratoses, on each of both treatment areas at least one
• Patients must be 18 years or older.

Exclusion criteria

• Age 17 years or younger
• lack of patient's informed consent for any of the two treatments
• contraindication for Co2 therapy or for photodynamic therapy
• skin infection in the treatment area

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: Single Blind