Comparative Study of the Effect of Dysport and Botox

Laserklinik Karlsruhe

Status and phase: Completed; Phase 4

Conditions: Aging

Treatments: Drug: botulinum toxin type A

Study type: Interventional

Funder types: Other

Identifiers

NCT00434863

CR-015-LK/2005

Details and patient eligibility

About

The purpose of this study is to test the effect of Dysport and Botox on forehead wrinkles and EMG activity.

Sex: All

Ages: 30 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• age between 30 and 70 years
• moderate to severe hyperfunctional forehead wrinkles at maximum contraction and at rest

Exclusion criteria

• application of botulinum toxin products for a period of 12 months prior to the study
• any significant health disturbances
• facial nerve palsy, and any facial conditions that could confound safety or efficacy results
• pregnancy and breast-feeding
• neuromuscular diseases
• drugs interfering with neuromuscular function (e.g. aminoglycosides)

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Single Group Assignment

Masking: Double Blind