Comparative Study of the Efficacy of Oral Versus Intravenous Hydration as a Preventive Measure of Contrast-induced Nephropathy (CIN) in Patients With Renal Insufficiency (RI) Grade III Under Study Conducting Computed Tomography (CT) (NICIR)

David Garcia Cinca

Status and phase

Completed

Phase 3

Conditions

Renal Insufficiency

Treatments

Drug: Bicarbonate endovenous hydratation

Drug: Saline endovenous hydratation

Other: Oral hydratation

Study type

Interventional

Funder types

Other

Identifiers

NCT02872155

NICIR

Details and patient eligibility

About

This study evaluates if oral hydratation is as effective as endovenous hydratation in the prophylaxis of contrast-induced nephropathy in patients renal insufficiency grade III under study conducting contrasted computed tomography.

Enrollment

264 patients

Sex

All

Ages

18 to 75 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Patients of both sexes over 18 years
Candidates for a study with computed tomography and intravenous contrast
A glomerular filtration rate between 30 and 45 mL / min including both determinations
They have signed the written informed consent after being informed of the objectives and the nature of the case or be unable to have the authorization or agreement of its

Exclusion criteria

refuse to participate in the study
pregnancy or lactation
Other risk factors for Contrast Induced Nephropathy: diabetes mellitus type I, have an age of 75 years or above, heart failure (defined by a scale New York Heart Association 3 or 4), hypotension (defined as systolic blood pressure <100), being treated with nephrotoxic medications.
Any disease or a history that, in the investigator's opinion, could confound the results of the study or pose an additional risk to patient treatment.