Comparative Study of Two Embryo Culture Systems (INCUBATE)

University Hospital Center (CHU) Dijon Bourgogne

Status: Completed

Conditions: Infertility

Treatments: Device: Embryo culture system without incorporated camera; Device: Embryoscope

Study type: Observational

Funder types: Other

Identifiers

NCT02722252

FAUQUE - INCUBATE

Details and patient eligibility

About

The centre for Medically-Assisted Procreation (MAP) of Dijon CHU has two high-technology embryo culture systems, with incubation characteristics that are potentially superior to those provided by classical culture systems. Indeed, these two systems, available in only two MAP centres in France, make it possible to maintain a stable temperature and gaseous environment during the in-vitro development of the embryos.

It is necessary to observe the development of the embryos to determine which embryos have the highest implantation potential. These observations are done from time to time by microscope for one system and continuously using an incorporated video camera for the other (cinematographic study). The MAP centre in Dijon wishes to compare the interest of these two systems.

Enrollment: 388 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Persons who have provided oral consent
• Attempt at In Vitro Fertilization with ICSI (IntraCytoplasmic Sperm Injection)
• At least 6 mature ovocytes to microinject

Exclusion criteria

• Persons not covered by national health insurance
• Attempt at In Vitro Fertilization (IVF)
• Fewer than 6 mature ovocytes
• Decision to transfer at the zygote stage during the multidisciplinary meeting
• Attempts made in a context of viral risk (both systems are in a virus risk-free zone)
• Attempts with surgically-harvested spermatozoa

Trial design

388 participants in 2 patient groups

Embryoscope group

Treatment:

Device: Embryoscope

Embryo culture without incorporated camera group

Treatment:

Device: Embryo culture system without incorporated camera