Comparative Trial of Standard Versus Low-dose Peg-Interferon Plus Ribavirin in the Treatment of Chronic Hepatitis C

Kyoto University

Status: Completed

Conditions: Hepatitis C, Chronic

Treatments: Drug: interferon-alfa-2b and ribavirin

Study type: Observational

Funder types: Other

Identifiers

NCT00216775

H16-697

Details and patient eligibility

About

The purpose of this study is to evaluate the efficacy and safety of low-dose interferon-alfa-2b plus ribavirin compared to the standard-dose of the same combination in patients with chronic hepatitis C.

Enrollment: 50 patients

Sex: All

Ages: 20 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Clinical diagnosis of Chronic Hepatitis C. Must be infected with genotype 1b viruses

Exclusion criteria

• Hemoglobin levels<8.5g/dL,
• Platelet counts<50,000/mm3,
• Total polymorphonuclear counts<1000/mm3
• Pregnancy,
• Renal dysfunction,