Compare Celecoxib and Ibuprofen Sr In The Management Of Acute Pain Post Orthopedic Or Gynecological Surgery

Viatris

Status and phase: Completed; Phase 3

Conditions: Pain, Postoperative

Treatments: Drug: celecoxib and ibuprofen SR

Study type: Interventional

Funder types: Industry

Identifiers

NCT00150280

A3191086

Details and patient eligibility

About

To validate the analgesic efficacy and safety of celecoxib compared with ibuprofen SR in the management of acute pain post orthopedic or gynecological surgery

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Undergone uncomplicated orthopedic surgery or abdominal gynecological surgery under epidural anesthesia
• Baseline pain intensity of more than 45 mm as measured by VAS and a severity of pain graded as moderate or severe on the categorical pain intensity scale

Exclusion criteria

• A previous history of intolerance or hypersensitivity to any NSAIDs, cyclooxygenase inhibitor, sulfonamides, or any analgesic, or to drugs with similar chemical structures

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind