Compare Effects of the Mirror Therapy and Robotic Mirror Therapy in Electroencephalography of Healthy Adults and Stroke Patients.

Chang Gung Medical Foundation

Status: Completed

Conditions: Healthy Adults; Stroke Patients

Treatments: Device: robotic hand

Study type: Interventional

Funder types: Other

Identifiers

NCT04236089

201900537A3

Details and patient eligibility

About

Mirror therapy has recently attracted increasing attention; however, most patients have the difficulties to perform mirror therapy due to limited imaginary ability. A mirror robotic hand system was developed, which consisted with a wearable exoskeletal hand, sensor glove, and a control box. The patient's unaffected hand wears the sensor glove, the affected hand wears the wearable exoskeleton hand, and the unaffected hand does the certain transitive and intransitive tasks as the mirror group, and then makes the affected hand do the same movements driven by the exoskeleton robotic hand. The investigators hypothesize that combining both approaches might facilitate the sensorimotor cortex that controls movement and might augment somatosensory input and further treatment efficacy. This study is aimed at investigating the effects of Mirror therapy and robotic mirror therapy on motor cortical activations in healthy adults and stroke patients using electroencephalography. All participants will perform the conditions of resting, moving right hand with or without robotic hand as the baseline data, then they will do mirror therapy using the right hand as active hand, or wearing robotic hand doing mirror therapy in random sequence. Electroencephalography (EEG) assessment will be done to assess the neurophysiologic effects of the different interventions. The investigators will use a questionnaire to assess the subjective opinion about the different interventions.

combined with execution (video AOE). The investigators will use the pair-t test to assess the within subjects differences in EEG and the questionnaire results.

This study will be done during 2020/02/01 - 2021/03/31.

Enrollment: 65 patients

Sex: All

Ages: 20 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• healthy adults: right handed, with normal upper extremity and cognition functions
• stroke patients:one side upper limb spasticity

Exclusion criteria

• 1. wrist weakness or deformity 2. skin problem 3. musculoskeletal injury of upper extremities

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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65 participants in 4 patient groups

mirror therapy of healthy adults

No Intervention group

Description:

Traditional mirror therapy in electroencephalography of healthy adults.

robotic mirror therapy of healthy adults

Experimental group

Description:

Robotic mirror therapy in electroencephalography of healthy adults.

Treatment:

Device: robotic hand

mirror therapy of stroke patients

No Intervention group

Description:

Traditional mirror therapy in electroencephalography of stroke patients.

robotic mirror therapy of stroke patients

Experimental group

Description:

Robotic mirror therapy in electroencephalography of stroke patients.

Treatment:

Device: robotic hand