Compare Hemodynamic Parameters of Propofol and Sevoflurane During CPB Time in Undergoing CABG to Avoid Lactate Level

Chaudhry Pervaiz Elahi Institute of Cardiology

Status: Unknown

Conditions: Hemodynamic Instability

Treatments: Drug: Propofol

Study type: Interventional

Funder types: Other

Identifiers

NCT05004545

CPEIC-06

Details and patient eligibility

About

Hemodynamic parameters and lactate level will be on CBP during CABG surgery patients.

Full description

Objective: To compare hemodynamic parameters of propofol and sevoflurane during cardiopulmonary bypass time in patients undergoing coronary artery bypass graft (CABG) surgery to avoid lactate level.

Methods: One hundred and twenty six patients scheduled for CABG from May 2017 to May 2018 will be included in this study. Non probability consecutive sampling will be used. Patients will be divided in two groups, propofol will be given to group 1, and sevoflurane will be given to group 2. Age, clamp time, bypass time, mean arterial blood pressure on bypass machine and lactate level will be compared between two groups. SPSS version 24 will used and p value ≤ 0.05 will be considered as significant.

Enrollment: 126 estimated patients

Sex: All

Ages: 20 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

CABG

Exclusion criteria

Emergency surgery

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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126 participants in 2 patient groups

group 1 Profol Infusion to CABG patients to check lactate level

Experimental group

Description:

Propofol infusion according to bodyweight will be given to check lactate level on CPB

Treatment:

Drug: Propofol

sevoflurane will be given to group 2 to check lacate level

Active Comparator group

Description:

Sevoflurane MAC % will be given to CABG patients to check lactate level

Treatment:

Drug: Propofol