Compare PPV With and Without Silicone Oil in Managing Postoperative Endophthalmitis (Endopthalmitis)

Benha University

Status: Completed

Conditions: Endophthalmitis Following Cataract Surgery

Treatments: Procedure: Silicone Oil; Procedure: Pars plana Vitrectomy

Study type: Interventional

Funder types: Other

Identifiers

NCT06990607

Endophthalmitis and silicone

Details and patient eligibility

About

Comparing PPV with and without silicone oil in managing postoperative endophthalmitis

Full description

The objective of this study is to compare the outcomes of PPV with silicone oil tamponade to PPV alone in patients with postoperative endophthalmitis by assessing visual acuity, and postoperative complications such as rhegmatogenous retinal detachment (RRD).

Enrollment: 40 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• adult patients (≥ 18 years) presenting with clinical manifestations of endophthalmitis after cataract surgery

Exclusion criteria

• patients with concurrent ocular or systemic conditions that could potentially confound study outcomes, such as active retinal diseases unrelated to endophthalmitis
• pre-existing poor visual prognosis due to conditions like advanced glaucoma or macular degeneration, or prior ocular surgery affecting the study

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

---

40 participants in 2 patient groups

Group I

Active Comparator group

Description:

Pars plana Vitrectomy Alone

Treatment:

Procedure: Pars plana Vitrectomy

Group II

Active Comparator group

Description:

Pars plana Vitrectomy with Silicone Oil

Treatment:

Procedure: Pars plana Vitrectomy

Procedure: Silicone Oil