Compare the Effect of Green Tea Mouthwash vs Chlorohexidine Mouthwash in Children With Plaque-induced Gingivitis

Cairo University (CU)

Status: Not yet enrolling

Conditions: Plaque Induced Gingivitis

Treatments: Drug: Chlorhexidine mouthwash; Drug: Green tea mouthwash

Study type: Interventional

Funder types: Other

Identifiers

NCT05803590

GT Mouthwash In Children

Details and patient eligibility

About

This study aims to assess and compare the effect of green tea mouthwash compared to chlorohexidine mouthwash in reducing gingivitis and plaque scores (in terms of plaque index and gingival index) in children with plaque-induced gingivitis.

Full description

This study aims to assess and compare the effect of green tea mouthwash compared to chlorohexidine mouthwash in reducing gingivitis and plaque scores (in terms of plaque index and gingival index) in children with plaque-induced gingivitis.

This study will be conducted in the outpatient clinics of the Pediatric Dentistry and Dental Public Health Department - Faculty of Dentistry, Cairo University - Egypt.

Patients attending the outpatient clinic in Pediatric Dentistry and Dental Public health Department - Faculty of Dentistry - Cairo University - Egypt will be screened until the target population is achieved.

Enrollment: 80 estimated patients

Sex: All

Ages: 10 to 14 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Children aged 10-14 years.
• Children with a gingival index score of ≥ 1 and a plaque index score of ≥ 1.
• Children in good medical health and free from major oral hard or soft tissue lesions. [Medically fit children (ASA I, II)].
• Children classified as cooperative or potentially cooperative according to Wright's classification of child behavior.
• Children mentally capable of communication.

Exclusion criteria

• Parental refusal for participation.
• Children under antibiotics treatment during the last six weeks prior to the study.
• Children wearing fixed or removable orthodontic devices.
• Patients who underwent oral prophylaxis in the last six months.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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80 participants in 2 patient groups

Green Tea Mouthwash ( intervention )

Active Comparator group

Description:

Green tea (GT), obtained from the extracts of a small plant, Camelia sinesis, is common worldwide. It is rich in flavonoids such as catechins and various other polyphenols, contributing to its antioxidant and anti-inflammatory properties. Green tea consumption is also associated with lower incidences of diabetes, cardiovascular disease, and obesity. Moreover, its antibacterial property aids in the reduction of bacterial colonization and thereby prevents oral diseases such as gingivitis, periodontal diseases, dental caries, and malodor . When used as a mouthwash, green tea preparations can obliterate bad breath by suppressing anaerobic bacteria and eradicating the production of volatile sulfur compounds. There is a lack of critically appraised summaries on the efficacy of green tea mouthwash for promoting dental hygiene .

Treatment:

Drug: Chlorhexidine mouthwash

Drug: Green tea mouthwash

Chlorhexidine Mouthwash ( control )

Experimental group

Description:

Chlorhexidine was developed in 1950 and is the most used anti-plaque agent. However, the long-term usage of chlorhexidine (CHX) is limited by altered taste perception and tooth staining with prolonged usage. Though CHX has been the gold standard mouthwash in controlling plaque formation, its undesirable side effects, such as the enhanced ability of calculus formation, bitter taste, and interference with taste, have inspired a search for alternatives

Treatment:

Drug: Chlorhexidine mouthwash

Drug: Green tea mouthwash