Compare the Effects of Fluticasone Furoate Nasal Spray vs Placebo in Patients With Nasal Polypoid Disease
Status and phase
Conditions
Treatments
Details and patient eligibility
About
Fluticasone furoate is being studied to determine whether treatment with a topical nasal steroid, in patients with existing nasal polyps , can not only improve symptoms but also suppress the recurrence of clinically significant nasal polyp obstruction and prevent surgical intervention.
Enrollment
Sex
Ages
Volunteers
Inclusion criteria
- Male and female patients 18-70 years of age, in general good health.
- Current evidence of nasal polyps on physical exam. 3) Able to understand the protocol and comply with instructions. 4) Have a negative urine pregnancy test in women of childbearing potential. 5) Women of childbearing potential must be on an acceptable method of birth control or willing to remain abstinent through the duration of the study.
Exclusion criteria
-
Are pregnant and/or breast-feeding.
-
History of alcohol or drug abuse in the past year.
-
Signs and symptoms suggestive of fulminant bacterial sinusitis (fever >101 F, persistent severe unilateral facial or tooth pain, facial swelling).
-
Allergies to nasal corticosteroids
-
.Other chronic significant medical illnesses 6) Maintenance oral prednisone therapy for other chronic medical conditions.
Trial design
Primary purpose
Allocation
Interventional model
Masking
7 participants in 2 patient groups, including a placebo group
Trial contacts and locations
Loading...
Data sourced from clinicaltrials.gov
Clinical trials
Research sites
Resources
Legal