Comparing 7 mm and 5 mm Implants Placed Immediately After Molar Extraction

Marco Esposito

Status: Active, not recruiting

Conditions: Immediate Implant Placement; Partial Edentulism in the Maxilla or in the Mandible

Treatments: Device: 7 mm Diameter Dental Implant; Device: 5 mm Diameter Dental Implant

Study type: Interventional

Funder types: NETWORK

Identifiers

NCT07041294

NR430PROT

Details and patient eligibility

About

This clinical study aims to evaluate the performance and long-term outcomes of immediate dental implants placed in molar sites after tooth extraction. Eligible patients will receive one implant and a single crown in a posterior area (first or second molar). The study will compare implant and crown success over a five-year period, tracking complications, bone changes, aesthetics, and patient satisfaction. Participants must be at least 18 years old and have sufficient bone to allow immediate implant placement. This research will provide important data on the safety and reliability of immediate implants in posterior areas.

Full description

This multicentre randomised controlled trial aims to compare the clinical outcomes of 7 mm versus 5 mm diameter dental implants placed immediately after tooth extraction in the molar region. The goal is to assess whether wider diameter implants offer any advantages in terms of implant survival, complications, bone preservation, and patient satisfaction, when placed in fresh extraction sockets.

A total of 70 patients requiring molar tooth extraction and immediate implant placement will be enrolled across 7 centers. Each participant will receive either a 5 mm or a 7 mm diameter implant, allocated randomly. Standardised surgical and prosthetic protocols will be followed.

Follow-up visits will assess implant stability, radiographic bone changes, and clinical outcomes over time. Patient-reported outcomes and complications will also be recorded to compare the two groups. Results will be reported at 1 and 5 years after loading.

This study may help clinicians make evidence-based decisions when choosing the diameter of implants in molar regions, particularly in immediate post-extraction situations.

Enrollment: 70 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• at least 18 years old
• able to sign an informed consent form
• requiring at least one immediate post-extractive implant in first and/or second molar sites
• sufficient bone to allow placement of an immediate implant at least 7 mm in length and 7 mm in diameter

Exclusion criteria

• general contraindications to implant surgery
• immunosuppressed or immunocompromised
• irradiation in the head or neck area
• uncontrolled diabetes
• pregnancy or lactation
• untreated periodontitis
• poor oral hygiene and motivation
• addiction to alcohol or drugs
• psychiatric disorders
• unrealistic expectations
• acute infection (abscess) in the site intended for implant placement
• necessity to lift the maxillary sinus epithelium
• unable to commit to 5-year follow-up post-loading
• under treatment or had previous treatment with intravenous amino-bisphosphonates
• lack of bony wall completely surrounding the future implant
• participation in other studies interfering with present protocol.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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70 participants in 2 patient groups

7 mm Diameter Implant

Experimental group

Description:

Participants receive a 7 mm diameter implant placed immediately after molar extraction.

Treatment:

Device: 7 mm Diameter Dental Implant

5 mm Diameter Implant

Active Comparator group

Description:

Participants receive a 5 mm diameter implant placed immediately after molar extraction.

Treatment:

Device: 5 mm Diameter Dental Implant