Comparing Acute Aerobic and Resistance Exercise (CAARE)

University of Houston

Status

Terminated

Conditions

Exercise Physiology

Treatments

Other: Resistance training exercise

Other: Aerobic training exercise

Study type

Interventional

Funder types

Other

Identifiers

NCT03794050

STUDY00001191

Details and patient eligibility

About

The purpose of this study is to determine the effect of age and fitness level on the physiological response to an acute bout of resistance or aerobic exercise.

Full description

Young and middle-aged to older adults who are physically active or not physically active will participate in two moderate to vigorous intensity exercise bouts: aerobic exercise and resistance training exercise. Blood will be collected to assess immune function and metabolism.

Enrollment

35 patients

Sex

All

Ages

18 to 75 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

"Young" Adults: ages 18-30
"Older" Adults: ages 55-75 and if a female postmenopausal
Participants classified as "trained" must participate in at least 30 minutes of moderate to vigorous intensity cardiovascular activity at least 3 days per week and engage in resistance training for all of the major muscle groups approximately 2 days / week. They must have upheld this activity for the past 3 months
Participants classified as "untrained" must be participating in less than 30 minutes of moderate to vigorous intensity cardiovascular activity and less than 2 days of resistance training per week for at least the last 3 months.

Exclusion criteria

Have any contraindications to moderate to vigorous exercise
Range of motion restrictions that would prevent them from participating in aerobic or resistance training with proper form (they must be ambulatory)
aking medications (prescription or over the counter) known to influence immune function, including daily NSAID's, beta blockers, statins, bisphosphonates, or steroids.
Have known cardiovascular, respiratory, metabolic, or renal disease, with the exception of controlled hypertension (as defined by resting BP below 140/90) and/or controlled asthma (self-reported).
Be pregnant
Be unable to complete all visits (i.e. must not be planning to leave the Houston area long-term before concluding their participation in the study which will span several weeks)
Fall outside of a BMI range of (18.5 - 30)
Consume alcohol or recreational drugs for 24h prior to visits
Older women cannot be pre-menopausal (must have not had a menses for at least 12 months)
Unable to speak or read English
Participants must not have scheduling conflicts that would prevent them from reporting to the laboratory of integrated physiology 4 times over the course of the study