Comparing Clinical Benefits of Gamma Knife and Microvascular Decompression for Trigeminal Neuralgia

University of Baghdad

Status: Completed

Conditions: Trigeminal Neuralgia

Treatments: Radiation: Gamma knife

Study type: Interventional

Funder types: Other

Identifiers

NCT03991039

Neurosciences-iraq

Details and patient eligibility

About

Clinical randomized study to compare the clinical effectiveness between two modalities of treatment of trigeminal neuralgia namely gamma knife radio surgery and microvascular decompression

Full description

A randomized prospective study conducted in The Neurosciences Hospital, Baghdad, from January 2016 to January 2018, patients had either GKR treatment or treated with MVD. The pain evaluated pre- and post-operatively using the Barrow Neurological Institute Pain Intensity scale (BNIPI), visual analog scale (VAS) and Brief Pain Inventory Facial (BPI-Facial) scoring systems. In GKR procedure, the trigeminal root entry zone targeted with a radiation dose of 80 Gy. MVD was performed using retro-sigmoid approach. Follow-up period for two years

Enrollment: 84 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• primary idiopathic trigeminal neuralgia

Exclusion criteria

• secondary trigeminal neuralgia

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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84 participants in 2 patient groups

Gamma knife group

Active Comparator group

Description:

Patients selected to be treated with gamma knife radiosurgery

Treatment:

Radiation: Gamma knife

MVD Group

Active Comparator group

Description:

Patients treated with microvascular decompression

Treatment:

Radiation: Gamma knife