Comparing Eye Pressure Using Maximal Tolerated Local Therapy or Systemic Acetazolamide

University of Cologne

Status: Completed

Conditions: Control of Elevated Eye Pressure by Local and Systemic Therapy

Treatments: Drug: Acetazolamide for glaucoma patients to lower eye pressure

Study type: Observational

Funder types: Other

Identifiers

NCT01274039

AcetazolamideTrialCologne

Details and patient eligibility

About

Local therapy for glaucoma is known to induce a conjunctival inflammation. Because of this, trabeculectomy is more likely to fail. The investigators exchange the local therapy by systemic therapy using acetazolamide and measure the eye pressure using local therapy and systemic therapy using acetazolamide. The investigators suspect an elevated eye pressure using acetazolamide compared to local therapy. In summary acetazolamide could be a better choice in reference to conjunctival inflammation, but a worse choice in reference to controlling eye pressure.

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with uncontrolled intraocular eye pressure
• Patients with planed trabeculectomy in 3 to 4 weeks

Exclusion criteria

• Patients not meeting the inclusion criteria
• Patients with known intolerance to acetazolamide

Trial design

0 participants in 1 patient group

Patient with a trabeculectomy planed

Treatment:

Drug: Acetazolamide for glaucoma patients to lower eye pressure