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Comparing Liquid Versus Solid Forms of Sugars and Whey Protein

U

University of Toronto

Status

Completed

Conditions

Diabetes
Obesity

Treatments

Other: the effect of solid vs. liquid forms of gelatin on appetite and food intake
Other: The effect of solid vs. liquid forms of whey protein on food intake
Other: Compare the effect of solid vs. liquid forms of sugars on satiety and food intake

Study type

Interventional

Funder types

Other
Industry

Identifiers

NCT01348685
Solid and liquid 1

Details and patient eligibility

About

To compare the effect of eating solid vs. drinking liquid forms of gelatin, sucrose and its component mixtures and whey protein on subjective appetite and food intake in young men.

Full description

Three randomized cross-over design experiments were used to compare the effect of solid and liquid forms of gelatin (6 g) in experiment 1, sucrose (75 g) and a mixture of 50% glucose/ 50% fructose (G50:F50) in experiment 2, and acid and sweet whey protein (50 g) in experiment 3 on healthy normal weight males . The controls were water (experiment 1 and 3) and calorie-free sweetened water with gelatin (sweet gelatin, experiment 1) or without gelatin (sweet control, experiment 2). Subjective average appetite was measured by visual analogue scales frequently over 1 h and ad libitum food intake was measured 1 h after the treatment consumptions.

Enrollment

43 patients

Sex

Male

Ages

19 to 28 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Healthy lean males with BMI between 18- 24.9 kg/m2 and an age range of 19 to 28 years were recruited for the three experiments.

Exclusion criteria

  • Diabetics (fasting blood glucose ≥ 7.0 mmol/L), smokers, breakfast skippers or dieters were excluded from the experiments. Individuals under medications or with a history of liver or kidney disease and major medical or surgical event within the last six months were excluded.

Trial design

Primary purpose

Prevention

Allocation

Randomized

Interventional model

Crossover Assignment

Masking

Single Blind

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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